Accelerometry during DBS

Set-up of combined accelerometry, electrophysiology and clinical assessments during DBS

In this study, we have evaluated the contribution of the acceleration measurement to aid in the optimal location of anatomical structures during deep brain stimulation surgery. Our primary objective in this pilot study, therefore, is to determine the characteristics of this method. The contribution can be dual: (1) Support for positioning using accelerometry with objective assessment of tremor or rigidity; (2) Improving the understanding of the physiopathology mechanisms and effect of chronic stimulation by correlating the accelerometer measurements with electrophysiological measurements and the patient's individual anatomy.

Fig. 1: Patient during DBS surgery with accelerometer on his wrist.

Fig. 2: (top) Acceleration Data with Stimulation Amplitude. (middle) Statistical parameters extracted from acceleration data compared to different stimulation amplitudes. (botom) Comparison of thresholds for one trajectory.